| Characteristic | Details |
|---|---|
| Active Ingredient | Domperidone 10mg |
| Dosage Form | Tablet |
| Therapeutic Class | Prokinetic Agent |
| Indications | Nausea, Vomiting, Gastric Motility Disorders |
| Learn More |
Pharmacokinetics
Domperidone, the active constituent in Generic Motilium 10mg, acts as a dopamine antagonist. It primarily affects the D2 receptors in the gastrointestinal tract. Its poor penetration through the blood-brain barrier minimizes central nervous system side effects. The medication is quickly absorbed orally. Peak plasma concentrations occur within 30 to 60 minutes post-ingestion.
The compound exhibits a half-life of around 7 hours in healthy subjects. The drug undergoes extensive hepatic metabolism. The cytochrome P450 enzymes CYP3A4 are involved in its biotransformation. The compound is primarily eliminated through feces, with renal excretion accounting for a smaller proportion. In hepatic dysfunction, dosage adjustments may be necessary.
Usage Guidelines for Generic Motilium
Generic Motilium 10mg should be used as directed by a healthcare professional. It is typically taken before meals to maximize efficacy. The recommended adult dose is one tablet, three times daily. Dosage for children should be determined by a physician based on body weight.
For individuals with renal impairment, dosing intervals may need extension. In case of any adverse symptoms, contact your healthcare provider immediately. Prolonged usage without medical supervision is not advised.
Clinical Indications
Generic Motilium is prescribed for managing nausea and vomiting. It is also beneficial for enhancing gastric motility. Patients with gastroparesis may find symptomatic relief through its use. It addresses discomfort caused by delayed gastric emptying.
It is crucial for users to adhere strictly to prescribed indications. Off-label usage should be avoided unless endorsed by a healthcare professional.
Missed Dose Instructions
If a dose of Generic Motilium 10mg is missed, it should be taken as soon as possible. However, if the time for the next scheduled dose is near, the missed dose should be skipped. Doubling doses to make up for missed ones is not recommended. Regularity in medication schedule enhances treatment efficacy.
Potential Adverse Effects
While Generic Motilium 10mg is generally well-tolerated, some users may experience side effects. Common adverse reactions include dry mouth, abdominal cramps, and dizziness. Serious side effects are rare but may include cardiac arrhythmias or allergic reactions.
Patients should report any unexpected symptoms to their healthcare provider. Regular monitoring may be warranted for those on long-term therapy.
Availability Without Prescription
In many jurisdictions, Generic Motilium is not available over the counter. A prescription from a licensed healthcare professional is often required. This ensures appropriate usage and monitoring.
Acquiring this medication through unauthorized sources can pose significant health risks. It is advised to consult a pharmacist or physician for any queries regarding its availability.
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