| Characteristic | Details |
|---|---|
| Active Ingredients | Sildenafil Citrate, Duloxetine |
| Dosage Options | 100mg Sildenafil, 30mg Duloxetine |
| Formulation | Tablet |
| Intended Use | Erectile Dysfunction, Premature Ejaculation |
| Prescription Requirement | Yes |
| Explore More | |
Pharmacokinetics
Malegra DXT Plus operates on the principles of pharmacokinetics that involve the absorption, distribution, metabolism, and excretion of its active constituents. Sildenafil Citrate, known for its role in vasodilation, is absorbed rapidly after oral ingestion. Its bioavailability stands at about 40%, which is optimal for treating erectile dysfunction. Duloxetine, on the other hand, affects neurotransmitter levels to manage premature ejaculation. Its bioavailability ranges from 32% to 80%. Both compounds reach peak plasma concentrations within two hours.
Post-ingestion, Sildenafil Citrate has a half-life of about four hours, facilitating its efficacy over a reasonable duration. Duloxetine possesses a longer half-life, extending up to 12 hours, which aids in prolonged sexual activity management. Liver metabolism, predominantly by cytochrome P450 enzymes, plays a significant role in both components’ breakdown. Excretion primarily occurs via renal and fecal routes.
Dosage Information
The standard dosage for Malegra DXT Plus is 100mg of Sildenafil Citrate and 30mg of Duloxetine. This combination addresses both erectile dysfunction and premature ejaculation effectively. Physicians typically recommend taking the tablet 30 minutes to an hour before sexual activity. Consuming no more than one dose per day is crucial to prevent adverse effects. Patients should swallow the tablet whole with water, avoiding high-fat meals that may delay absorption.
Adjustments in dosage may be necessary for individuals with hepatic or renal impairments. Consulting healthcare providers ensures the right balance between efficacy and safety. If side effects manifest, medical attention becomes imperative.
Who Can and Cannot Take Malegra DXT Plus
Malegra DXT Plus serves adult men struggling with erectile dysfunction and premature ejaculation. However, it remains unsuitable for women and children. Individuals with cardiovascular conditions, such as severe heart failure or recent myocardial infarction, should avoid this medication. Those with hypersensitivity to Sildenafil or Duloxetine must refrain from use.
Patients taking nitrates, nitric oxide donors, or certain antidepressants face contraindications due to potential interactions. Men with severe liver impairment should seek alternatives. Professional guidance aids in determining suitability.
Missed Dose
Since Malegra DXT Plus is used as needed, missing a dose does not usually apply. However, adherence to dosage timing ensures optimal results. Skipping doses with intent to catch up later is inadvisable. Overdosing may lead to severe health complications.
In scenarios where a missed dose disrupts routine, consulting healthcare professionals helps mitigate risks. They provide tailored advice for maintaining therapeutic efficacy.
Effects of Malegra DXT Plus
Malegra DXT Plus effectively enhances erectile function while managing premature ejaculation. Sildenafil Citrate increases blood flow to the penis, ensuring firm erections. Duloxetine delays ejaculation by modulating serotonin levels. The dual action results in improved sexual performance and satisfaction.
Common side effects include headaches, dizziness, and flushing. More severe reactions, although rare, demand immediate medical intervention. Regular monitoring helps detect adverse effects early.
Malegra DXT Plus for Sale Online
Purchasing Malegra DXT Plus online offers convenience but requires caution. Authorized pharmaceutical vendors ensure product authenticity and safety. Comparing prices across platforms allows for economical choices.
Online shopping necessitates verifying seller credentials. Seeking licensed and regulated outlets protects consumers from counterfeit products. Consulting with healthcare providers before purchase aids in informed decision-making.
| Parameter | Details |
|---|---|
| Onset of Action | 30-60 minutes |
| Duration of Effect | Up to 4 hours |
| Food Interaction | High-fat meals may delay effect |
- Consult healthcare providers before use
- Verify online vendor credentials
- Adhere to prescribed dosage
- Monitor for side effects
- Avoid concurrent use with contraindicated drugs
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